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Article

Interaction between Helicobacter pylori and host genetic variants in gastric carcinogenesis.

Future oncology (London, England) - 1 Sept 2016

Jia Zhi-Fang, Zhang Song-Ling, Cao Xue-Yuan, Zhou Bao-Sen, Jiang Jing

Abstract excerpt

Helicobacter pylori (H. pylori) is the definite carcinogen of gastric cancer. H. pylori infection induces chronic inflammation, causes DNA damage and aberrant methylation of genes and these pathways are involved in H. pylori-related gastric carcinogenesis. Polymorphisms of the genes involved in these pathways could alter susceptibility to gastric cancer. In this mini review, we focused on the role of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27324311
DOI: 10.2217/fon-2016-0233

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