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Polymorphisms of TGFBR1, TLR4 are associated with prognosis of gastric cancer in a Chinese population

20 Nov 2018

Abstract excerpt

Helicobacter pylori ( H. pylori )-induced gastric cancer is an intricate progression of immune response against H. pylori infection. IL-16, TGF-β1 and TLR4 pathways were the mediators involved in the immune response. We hypothesized that genetic variations in genes of these pathways have potential susceptibility to gastric cancer risk, and predict clinical outcomes of patients. To investigate the susceptibility...

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PMID: 30479570
DOI: 10.1186/s12935-018-0682-0

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