Article
Polymorphisms of tumor-related genes IL-10, PSCA, MTRR and NOC3L are associated with the risk of gastric cancer in the Chinese Han population.
Cancer epidemiology - 1 Dec 2012
Yuan Li Juan, Jin Tian Bo, Yin Ji Kai, Du Xi Lin, Wang Qing, Dong Rui, Wang Sheng Zhi, Cui Yan, Chen Chao, Lu Jian Guo
Abstract excerpt
BACKGROUND: Gastric cancer is the fourth most common cancer in the world. Environmental and genetic factors both play critical roles in the etiology of gastric cancer. Hundreds of SNPs have been identified to have association with the risk of gastric cancer in many races. In this study, 25 SNPs in genes for IL-10, IL-1B, MTRR, TNF-а, PSCA, PLCE1 and NOC3L were analyzed to further evaluate their associations with...
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