Article
The within-host dynamics of African trypanosome infections.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 19 Aug 2015
Matthews Keith R, McCulloch Richard, Morrison Liam J
Abstract excerpt
African trypanosomes are single-celled protozoan parasites that are capable of long-term survival while living extracellularly in the bloodstream and tissues of mammalian hosts. Prolonged infections are possible because trypanosomes undergo antigenic variation-the expression of a large repertoire of antigenically distinct surface coats, which allows the parasite population to evade antibody-mediated elimination....
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