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Article

A Host-Pathogen Interaction Reduced to First Principles: Antigenic Variation in T. brucei.

Results and problems in cell differentiation - 1 Jan 2015

Hovel-Miner Galadriel, Mugnier Monica, Papavasiliou F Nina, Pinger Jason, Schulz Danae

Abstract excerpt

Antigenic variation is a common microbial survival strategy, powered by diversity in expressed surface antigens across the pathogen population over the course of infection. Even so, among pathogens, African trypanosomes have the most comprehensive system of antigenic variation described. African trypanosomes (Trypanosoma brucei spp.) are unicellular parasites native to sub-Saharan Africa, and the causative agents...

Topics

Animals
Genetic Variation
Host-Parasite Interactions
Humans
Insect Vectors
Trypanosoma brucei brucei
Trypanosomiasis, African
Variant Surface Glycoproteins, Trypanosoma

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26537376
DOI: 10.1007/978-3-319-20819-0_2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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