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African trypanosomes: the genome and adaptations for immune evasion

24 Oct 2011

Abstract excerpt

The African trypanosome Trypanosoma brucei is a flagellated unicellular parasite transmitted by tsetse flies that causes African sleeping sickness in sub-Saharan Africa. Trypanosomes are highly adapted for life in the hostile environment of the mammalian bloodstream, and have various adaptations to their cell biology that facilitate immune evasion. These include a specialized morphology, with most nutrient uptake...

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PMID: 22023441
DOI: 10.1042/bse0510047

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