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Article

Isolation and characterisation of transport-defective substrate-binding mutants of the tetracycline antiporter TetA(B).

Biochimica et biophysica acta - 1 Oct 2015

Wright David J, Tate Christopher G

Abstract excerpt

The tetracycline antiporter TetA(B) is a member of the Major Facilitator Superfamily which confers tetracycline resistance to cells by coupling the efflux of tetracycline to the influx of protons down their chemical potential gradient. Although it is a medically important transporter, its structure has yet to be determined. One possibility for why this has proven difficult is that the transporter may be...

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Identifiers

PMID: 26143388
DOI: 10.1016/j.bbamem.2015.06.026
PMCID: PMC4579554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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