Article
Identification of structural and functional domains of the tetracycline efflux protein TetA(P) from Clostridium perfringens.
Microbiology (Reading, England) - 1 Oct 1999
Bannam T L, Rood J I
Abstract excerpt
The Clostridium perfringens tetracycline-resistance protein, TetA(P), is an integral inner-membrane protein that mediates the active efflux of tetracycline from the cell. TetA(P) acts as an antiporter, presumably transporting a divalent cation-tetracycline complex in exchange for a proton, and is predicted to have 12 transmembrane domains (TMDs). Two glutamate residues that are located in predicted TMD 2 were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
