Article
Advanced Proteogenomic Analysis Reveals Multiple Peptide Mutations and Complex Immunoglobulin Peptides in Colon Cancer.
Journal of proteome research - 4 Sept 2015
Woo Sunghee, Cha Seong Won, Bonissone Stefano, Na Seungjin, Tabb David L, Pevzner Pavel A, Bafna Vineet
Abstract excerpt
Aiming toward an improved understanding of the regulation of proteins in cancer, recent studies from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) have focused on analyzing cancer tissue using proteomic technologies and workflows. Although many proteogenomics approaches for the study of cancer samples have been proposed, serious methodological challenges remain, especially in the identification of...
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