Article
Identifying mutated proteins secreted by colon cancer cell lines using mass spectrometry.
Journal of proteomics - 5 Dec 2012
Mathivanan Suresh, Ji Hong, Tauro Bow J, Chen Yuan-Shou, Simpson Richard J
Abstract excerpt
Secreted proteins encoded by mutated genes (mutant proteins) are a particularly rich source of biomarkers being not only components of the cancer secretome but also actually implicated in tumorigenesis. One of the challenges of proteomics-driven biomarker discovery research is that the bulk of se...
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