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Immune complexome analysis reveals the specific and frequent presence of immune complex antigens in lung cancer patients: A pilot study

29 Sept 2016

Abstract excerpt

Cancer immunotherapies such as antibodies targeting T cell checkpoints, or adaptive tumor-infiltrating lymphocyte (TIL) transfer, have been developed to boost the endogenous immune response against human malignancies. However, activation of T cells by such antibodies can lead to the risk of autoimmune diseases. Also, the selection of tumor-reactive T cells for TIL relies on information regarding mutated antigens...

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PMID: 27685836
DOI: 10.1002/ijc.30455

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