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Immunopeptidomic Analyses of Colorectal Cancers With and Without Microsatellite Instability

1 Apr 2022

Abstract excerpt

Colorectal cancer is the second leading cause of cancer death worldwide, and the incidence of this disease is expected to increase as global socioeconomic changes occur. Immune checkpoint inhibition therapy is effective in treating a minority of colorectal cancer tumors; however, microsatellite stable tumors do not respond well to this treatment. Emerging cancer immunotherapeutic strategies aim to activate a...

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PMID: 35367648
DOI: 10.1016/j.mcpro.2022.100228

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