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Proteogenomics meets cancer immunology: mass spectrometric discovery and analysis of neoantigens

15 Jul 2015

Abstract excerpt

Cancer proteogenomics is an emerging field that aims to identify and quantify protein sequence changes associated with the cancer genome. Besides being involved in cancer development and progression, such protein variants may serve as neoantigens, which provide the T-cell response against tumors. Mass spectrometry-based proteogenomics may be a promising tool for finding neoantigens in individual specimens. It is...

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PMID: 26175083
DOI: 10.1586/14789450.2015.1070100

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