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Beta-cell Specific Autoantibodies: Are they Just an Indicator of Type 1 Diabetes?

16 May 2017

Abstract excerpt

BACKGROUND: Autoantibodies (AAbs) against islet autoantigens (AAgs) are used for type 1 diabetes (T1D) diagnosis and prediction. Islet-specific AAbs usually appear early in life and may fluctuate in terms of number and titer sometimes for over 20 years before T1D develops. Whereas their predictive power is high for pediatric subjects with high genetic risk who rapidly progress to multiple AAb positivity, they are...

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PMID: 27117244
DOI: 10.2174/1573399812666160427104157

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