Article
Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children.
JAMA - 19 Jun 2013
Ziegler Anette G, Rewers Marian, Simell Olli, Simell Tuula, Lempainen Johanna, Steck Andrea, Winkler Christiane, Ilonen Jorma, Veijola Riitta, Knip Mikael, Bonifacio Ezio, Eisenbarth George S
Abstract excerpt
IMPORTANCE: Type 1 diabetes usually has a preclinical phase identified by circulating islet autoantibodies, but the rate of progression to diabetes after seroconversion to islet autoantibodies is uncertain. OBJECTIVE: To determine the rate of progression to diabetes after islet autoantibody seroconversion. DESIGN, SETTING, AND PARTICIPANTS: Data were pooled from prospective cohort studies performed in Colorado...
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