Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.

Diabetologia - 1 May 2015

Krischer Jeffrey P, Lynch Kristian F, Schatz Desmond A, Ilonen Jorma, Lernmark Åke, Hagopian William A, Rewers Marian J, She Jin-Xiong, Simell Olli G, Toppari Jorma, Ziegler Anette-G, Akolkar Beena, Bonifacio Ezio

Abstract excerpt

AIMS/HYPOTHESIS: Islet autoantibodies, in addition to elevated blood glucose, define type 1 diabetes. These autoantibodies are detectable for a variable period of time before diabetes onset. Thus, the occurrence of islet autoantibodies is associated with the beginning of the disease process. The age at, and order in, which autoantibodies appear may be associated with different genetic backgrounds or environmental...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Diabetes Mellitus, Type 1

Share to Genetic Predisposition to Disease

Share to HLA-DQ Antigens

Share to Insulin

Share to Islets of Langerhans

Source

Open in PubMed Open full text

Identifiers

PMID: 25660258
DOI: 10.1007/s00125-015-3514-y
PMCID: PMC4393776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.PMID 25660258Read ↗

Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.Semantic proximity Read ↗

Age-related islet autoantibody incidence in offspring of patients with type 1 diabetes.Semantic proximity Read ↗

Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study.Semantic proximity Read ↗

Autoimmune Diabetes From Childhood to Adulthood: The Role of Pancreatic Autoantibodies and HLA-DRB1 Genotype.Semantic proximity Read ↗

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children.Semantic proximity Read ↗

Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).Semantic proximity Read ↗

Age at development of type 1 diabetes- and celiac disease-associated antibodies and clinical disease in genetically susceptible children observed from birth.Semantic proximity Read ↗

Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children.Semantic proximity Read ↗

The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.Semantic proximity Read ↗

Brief communication: early appearance of islet autoantibodies predicts childhood type 1 diabetes in offspring of diabetic parents.Semantic proximity Read ↗

Late-onset islet autoimmunity in childhood: the Diabetes Autoimmunity Study in the Young (DAISY).Semantic proximity Read ↗

Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.