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Article

Mitochondrial variants in MT-CO2 and D-loop instability are involved in MUTYH-associated polyposis.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2015

Errichiello Edoardo, Balsamo Antonella, Cerni Marianna, Venesio Tiziana

Abstract excerpt

UNLABELLED: Mitochondrial DNA alterations have been widely reported in different human tumours, including colorectal carcinoma, but their mutational spectrum and pathogenic role in specific subsets of patients with polyposis syndromes have been poorly investigated. We compared the breadth of somatic variants across the mitochondrial genome of MUTYH-associated polyposis (MAP) patients with homogeneous groups of...

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Source

Identifiers

PMID: 26138249
DOI: 10.1007/s00109-015-1312-0

Genes

FAP
MUTYH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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