Article
The landscape of mitochondrial DNA variation in human colorectal cancer on the background of phylogenetic knowledge.
Biochimica et biophysica acta - 1 Apr 2012
Skonieczna Katarzyna, Malyarchuk Boris A, Grzybowski Tomasz
Abstract excerpt
Recently, an increasing number of studies indicate that mutations in mitochondrial genome may contribute to cancer development or metastasis. Hence, it is important to determine whether the mitochondrial DNA might be a good, clinically applicable marker of cancer. This review describes hereditary as well as somatic mutations reported in mitochondrial DNA of colorectal cancer cells. We showed here that the entire...
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