Article
Exploring the Balance between DNA Pressure and Capsid Stability in Herpesviruses and Phages
2 Jul 2015
Abstract excerpt
UNLABELLED: We have recently shown in both herpesviruses and phages that packaged viral DNA creates a pressure of tens of atmospheres pushing against the interior capsid wall. For the first time, using differential scanning microcalorimetry, we directly measured the energy powering the release of pressurized DNA from the capsid. Furthermore, using a new calorimetric assay to accurately determine the temperature...
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