Article
Peering down the barrel of a bacteriophage portal: the genome packaging and release valve in p22.
Structure (London, England : 1993) - 13 Apr 2011
Tang Jinghua, Lander Gabriel C, Olia Adam S, Olia Adam, Li Rui, Casjens Sherwood, Prevelige Peter, Cingolani Gino, Baker Timothy S, Johnson John E
Abstract excerpt
The encapsidated genome in all double-strand DNA bacteriophages is packaged to liquid crystalline density through a unique vertex in the procapsid assembly intermediate, which has a portal protein dodecamer in place of five coat protein subunits. The portal orchestrates DNA packaging and exit, through a series of varying interactions with the scaffolding, terminase, and closure proteins. Here, we report an...
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