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Ionic switch controls the DNA state in phage λ

19 Jun 2015

Abstract excerpt

We have recently found that DNA packaged in phage λ undergoes a disordering transition triggered by temperature, which results in increased genome mobility. This solid-to-fluid like DNA transition markedly increases the number of infectious λ particles facilitating infection. However, the structural transition strongly depends on temperature and ionic conditions in the surrounding medium. Using titration...

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PMID: 26092697
DOI: 10.1093/nar/gkv611

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