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Biophysics of viral infectivity: matching genome length with capsid size

1 Nov 2007

Abstract excerpt

In this review, we discuss recent advances in biophysical virology, presenting experimental and theoretical studies on the physical properties of viruses. We focus on the double-stranded (ds) DNA bacteriophages as model systems for all of the dsDNA viruses both prokaryotic and eukaryotic. Recent studies demonstrate that the DNA packaged into a viral capsid is highly pressurized, which provides a force for the...

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PMID: 18423102
DOI: 10.1017/s0033583508004666

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