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Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold.

mBio - 17 Oct 2017

Hua Jianfei, Huet Alexis, Lopez Carlos A, Toropova Katerina, Pope Welkin H, Duda Robert L, Hendrix Roger W, Conway James F

Abstract excerpt

Large icosahedral viruses that infect bacteria represent an extreme of the coevolution of capsids and the genomes they accommodate. One subset of these large viruses is the jumbophages, tailed phages with double-stranded DNA genomes of at least 200,000 bp. We explored the mechanism leading to increased capsid and genome sizes by characterizing structures of several jumbophage capsids and the DNA packaged within...

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Identifiers

PMID: 29042498
DOI: 10.1128/mBio.01579-17
PMCID: PMC5646251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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