Article
Mitochondrial DNA sequence variation in multiple sclerosis.
Neurology - 28 Jul 2015
Tranah Gregory J, Santaniello Adam, Caillier Stacy J, D'Alfonso Sandra, Martinelli Boneschi Filippo, Hauser Stephen L, Oksenberg Jorge R
Abstract excerpt
OBJECTIVE: To assess the influence of common mitochondrial DNA (mtDNA) sequence variation on multiple sclerosis (MS) risk in cases and controls part of an international consortium. METHODS: We analyzed 115 high-quality mtDNA variants and common haplogroups from a previously published genome-wide association study among 7,391 cases from the International Multiple Sclerosis Genetics Consortium and 14,568 controls...
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