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Article

Mitochondrial complex I gene variations; as a potential genetic risk factor in pathogenesis of multiple sclerosis.

Journal of the neurological sciences - 15 Oct 2014

Poursadegh Zonouzi Ahmad, Ghorbian Saeid, Abkar Morteza, Poursadegh Zonouzi Ali Akbar, Azadi Ali

Abstract excerpt

BACKGROUND AND PURPOSE: Multiple sclerosis (MS) is an autoimmune-mediated inflammatory and debilitating disease of the central nervous system. Several investigations have suggested that the mitochondrial DNA encoded subunits of complex I gene variations are involved in the progression of MS. In this study, we investigated the possible association between mitochondrial complex I gene variations and MS in a...

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Identifiers

PMID: 25172194
DOI: 10.1016/j.jns.2014.07.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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