Article

CD4<sup>+</sup>T cell mitochondrial genotype in Multiple Sclerosis: a cross-sectional and longitudinal analysis

2023-03-27

Abstract excerpt

2. Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system (CNS), with a largely unknown etiology, where mitochondrial dysfunction significantly contributes to neuroaxonal loss and brain atrophy. Mirroring the CNS, peripheral immune cells from patients with MS, particularly CD4 + T cells, show inappropriate mitochondrial phenotypes and/or oxidative phosphorylation (OxPho...

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Literature Corpus work: 01d8b844-b4d5-5ab5-b18f-daa014d5bac4
DOI: 10.1101/2023.03.22.23287580

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