Article
[Variability of the Mitochondrial Genome and Development of the Primary Progressing form of Multiple Sclerosis].
Molekuliarnaia biologiia - 1 Jan 2000
Kozin M S, Kulakova O G, Kiselev I S, Boyko A N, Favorova O O
Abstract excerpt
Recently, it has been shown that dysfunction of mitochondria is an important component of the molecular mechanisms of the development of many neurodegenerative diseases. These include multiple sclerosis, a chronic autoimmune and neurodegenerative disease of the central nervous system, which is characterized by clinical heterogeneity. The role of genetic variability of mitochondrial DNA in the development of...
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