Article
Systematic Review of Candidate Single-nucleotide Polymorphisms as Biomarkers for Responsiveness to Neoadjuvant Chemoradiation for Rectal Cancer.
Anticancer research - 1 Jul 2015
Maring Elizabeth D, Tawadros Patrick S, Steer Clifford J, Lee Janet T
Abstract excerpt
BACKGROUND/AIM: Treatment of rectal cancer has improved significantly with the addition of neoadjuvant chemoradiation. Certain patients have experienced a complete pathological response to chemoradiation, as observed in surgically resected tissue samples, thus calling into question the necessity of radical surgery in this population of patients. Pharmacogenetic studies now implicate the role that genetic...
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