Article
Identification of a biomarker profile associated with resistance to neoadjuvant chemoradiation therapy in rectal cancer.
Annals of surgery - 1 Sept 2011
Garcia-Aguilar Julio, Chen Zhenbin, Smith David D, Li Wenyan, Madoff Robert D, Cataldo Peter, Marcet Jorge, Pastor Carlos
Abstract excerpt
OBJECTIVE: To identify a biomarker profile associated with tumor response to chemoradiation (CRT) in locally advanced rectal cancer. BACKGROUND: Rectal cancer response to neoadjuvant CRT is variable. Whereas some patients have a minimal response, others achieve a pathologic complete response (pCR) and have no viable cancer cells in their surgical specimens. Identifying biomarkers of response will help select...
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