Article
MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia.
Neuroscience letters - 18 Aug 2015
Patel Veena S, Kelly Sinead, Wright Carrie, Gupta Cota Navin, Arias-Vasquez Alejandro, Perrone-Bizzozero Nora, Ehrlich Stefan, Wang Lei, Bustillo Juan R, Morris Derek, Corvin Aiden, Cannon Dara M, McDonald Colm, Donohoe Gary, Calhoun Vince D, Turner Jessica A
Abstract excerpt
Genome-wide association studies implicate the MIR137HG risk variant rs1625579 (MIR137HGrv) within the host gene for microRNA-137 as a potential regulator of schizophrenia susceptibility. We examined the influence of MIR137HGrv genotype on 17 subcortical and callosal volumes in a large sample of individuals with schizophrenia and healthy controls (n=841). Although the volumes were overall reduced relative to...
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