Article
Genome-wide schizophrenia variant at MIR137 does not impact white matter microstructure in healthy participants.
Neuroscience letters - 27 Jun 2014
Kelly Sinead, Morris Derek W, Mothersill Omar, Rose Emma Jane, Fahey Ciara, O'Brien Carol, O'Hanlon Erik, Gill Michael, Corvin Aiden P, Donohoe Gary
Abstract excerpt
A single nucleotide polymorphism (SNP rs1625579) within the micro-RNA 137 (MIR137) gene recently achieved strong genome-wide association with schizophrenia (SZ). However, the mechanisms by which SZ risk may be mediated by this variant are unknown. As miRNAs have the potential to influence oligodendrocyte development, we investigated whether this SNP was associated with variability in white matter (WM)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
