Article
Effects of MIR137 on fronto-amygdala functional connectivity.
NeuroImage - 15 Apr 2014
Mothersill Omar, Morris Derek W, Kelly Sinead, Rose Emma Jane, Fahey Ciara, O'Brien Carol, Lyne Ronan, Reilly Richard, Gill Michael, Corvin Aiden P, Donohoe Gary
Abstract excerpt
BACKGROUND: MIR137 is implicated in brain development and encodes a microRNA that regulates neuronal maturation and adult neurogenesis. Recently, a common genetic variant within MIR137 showed genome wide evidence of association with schizophrenia, and with altered amygdala activation in those at genetic risk for schizophrenia. Following this evidence, we investigated the effects of MIR137 genotype on neuronal...
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