Article
Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2012
Whalley Heather C, Papmeyer Martina, Romaniuk Liana, Sprooten Emma, Johnstone Eve C, Hall Jeremy, Lawrie Stephen M, Evans Kathryn L, Blumberg Hilary P, Sussmann Jessika E, McIntosh Andrew M
Abstract excerpt
A recent 'mega-analysis' combining genome-wide association study data from over 40,000 individuals identified novel genetic loci associated with schizophrenia (SCZ) at genome-wide significance level. The strongest finding was a locus within an intron of a putative primary transcript for microRNA MIR137. In the current study, we examine the impact of variation at this locus (rs1625579, G/T; where T is the common...
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