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Article

eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes.

Allergy - 1 Oct 2015

Li X, Hastie A T, Hawkins G A, Moore W C, Ampleford E J, Milosevic J, Li H, Busse W W, Erzurum S C, Kaminski N, Wenzel S E, Meyers D A, Bleecker E R

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWASs) have identified various genes associated with asthma, yet, causal genes or single nucleotide polymorphisms (SNPs) remain elusive. We sought to dissect functional genes/SNPs for asthma by combining expression quantitative trait loci (eQTLs) and GWASs. METHODS: Cis-eQTL analyses of 34 asthma genes were performed in cells from human bronchial epithelial biopsy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26119467
DOI: 10.1111/all.12683
PMCID: PMC4583797

Genes

TSLP
GSDMB
ORMDL3
CDHR3
DEXI
ZBTB10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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