Article
Airway Epithelial Expression Quantitative Trait Loci Reveal Genes Underlying Asthma and Other Airway Diseases.
American journal of respiratory cell and molecular biology - 1 Feb 2016
Luo Wei, Obeidat Ma'en, Di Narzo Antonio Fabio, Chen Rong, Sin Don D, Paré Peter D, Hao Ke
Abstract excerpt
Genome-wide association studies (GWASs) have identified loci that are robustly associated with asthma and related phenotypes; however, the molecular mechanisms underlying these associations need to be explored. The most relevant tissues to study the functional consequences of asthma are the airways. We used publically available data to derive expression quantitative trait loci (eQTLs) for human epithelial cells...
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