Article
Expression of asthma susceptibility genes in bronchial epithelial cells and bronchial alveolar lavage in the Severe Asthma Research Program (SARP) cohort.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Oct 2016
Li Xingnan, Hawkins Gregory A, Moore Wendy C, Hastie Annette T, Ampleford Elizabeth J, Milosevic Jadranka, Li Huashi, Busse William W, Erzurum Serpil C, Kaminski Naftali, Wenzel Sally E, Bleecker Eugene R, Meyers Deborah A
Abstract excerpt
OBJECTIVE: Genome-wide association studies (GWASs) have identified genes associated with asthma, however expression of these genes in asthma-relevant tissues has not been studied. This study tested expression and correlation between GWAS-identified asthma genes and asthma or asthma severity. METHODS: Correlation analyses of expression levels of GWAS-identified asthma genes and asthma-related biomarkers were...
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