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Article

Multiplex pyrosequencing assay using AdvISER-MH-PYRO algorithm: a case for rapid and cost-effective genotyping analysis of prostate cancer risk-associated SNPs.

BMC medical genetics - 25 Jun 2015

Ambroise Jérôme, Butoescu Valentina, Robert Annie, Tombal Bertrand, Gala Jean-Luc

Abstract excerpt

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) identified in Genome Wide Association Studies (GWAS) have generally moderate association with related complex diseases. Accordingly, Multilocus Genetic Risk Scores (MGRSs) have been computed in previous studies in order to assess the cumulative association of multiple SNPs. When several SNPs have to be genotyped for each patient, using successive uniplex...

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PMID: 26108440
DOI: 10.1186/s12881-015-0186-x
PMCID: PMC4630960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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