Article
Multigene panels in prostate cancer risk assessment: a systematic review.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jun 2016
Little Julian, Wilson Brenda, Carter Ron, Walker Kate, Santaguida Pasqualina, Tomiak Eva, Beyene Joseph, Usman Ali Muhammad, Raina Parminder
Abstract excerpt
PURPOSE: Single-nucleotide polymorphism (SNP) panel tests have been proposed for use in the detection of, and prediction of risk for, prostate cancer and as prognostic indicator in affected men. A systematic review was undertaken to address three research questions to evaluate the analytic validity, clinical validity, clinical utility, and prognostic validity of SNP-based panels. METHODS: Data sources comprised...
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