Article

Absolute Quantitation of DNA Methylation of 28 Candidate Genes in Prostate Cancer Using Pyrosequencing

2011-01-01

Abstract excerpt

Aberrant DNA methylation plays a pivotal role in carcinogenesis and its mapping is likely to provide biomarkers for improved diagnostic and risk assessment in prostate cancer (PCa). We quantified and compared absolute methylation levels among 28 candidate genes in 48 PCa and 29 benign prostate hyperplasia (BPH) samples using the pyrosequencing (PSQ) method to identify genes with diagnostic and prognostic potential...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 88b7a680-d493-5182-921c-72eec46a94c8
DOI: 10.1155/2011/157829

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Absolute Quantitation of DNA Methylation of 28 Candidate Genes in Prostate Cancer Using PyrosequencingDOI 10.1155/2011/157829Read

Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing.Semantic proximity Read

Age-Related DNA Methylation Changes in Normal Human Prostate TissuesSemantic proximity Read

Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian MenSemantic proximity Read

Epigenetic Markers for Molecular Detection of Prostate CancerSemantic proximity Read

Multiple Highly Methylated CpG Sites as Potential Epigenetic Markers for the Diagnosis of Prostate CancerSemantic proximity Read

DNA methylation alterations in prostate cancer: from diagnosis to treatmentSemantic proximity Read

Global Methylation Profiling for Risk Prediction of Prostate CancerSemantic proximity Read

Aberrant DNA Methylation and Prostate CancerSemantic proximity Read

Epigenomic profiling of DNA methylation in paired prostate cancer versus adjacent benign tissueSemantic proximity Read

Hypermethylation of CpG Islands in Primary and Metastatic Human Prostate CancerSemantic proximity Read

DNA Methylation Changes Correlate with Gleason Score and Tumor Stage in Prostate CancerSemantic proximity Read

Diagnostic and prognostic information in prostate cancer with the help of a small set of hypermethylated gene loci.Semantic proximity Read