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Article

Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing.

1 Jan 2011

Abstract excerpt

Aberrant DNA methylation plays a pivotal role in carcinogenesis and its mapping is likely to provide biomarkers for improved diagnostic and risk assessment in prostate cancer (PCa). We quantified and compared absolute methylation levels among 28 candidate genes in 48 PCa and 29 benign prostate hyperplasia (BPH) samples using the pyrosequencing (PSQ) method to identify genes with diagnostic and prognostic...

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Share to Cancer-related gene regulation
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PMID: 21694441
DOI: 10.3233/dma-2011-0790

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