Article
When is a genetic test suitable for prime time? Predicting the risk of prostate cancer as a case-example.
Public health genomics - 1 Jan 2010
Li-Wan-Po A, Farndon P, Cooley C, Lithgow J
Abstract excerpt
Advances in genomics promise to deliver personalized medicine both for prevention and treatment of disease. Considerable effort is being directed towards translating observed associations between various genetic variants, such as single nucleotide polymorphisms (SNPs), and disease or drug response into clinically useful genetic tests. Unfortunately, because reported associations are usually weak or moderate,...
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