Effects of genotype on rates of substitution during experimental evolution.

Abstract excerpt

Rates of molecular evolution may vary widely between populations, yet the causes of this variation are still incompletely understood. Genetic differences between populations may make an important contribution to variation in rates of evolution, owing to differences in fitness, population size, mutation rates, or in the distribution of fitness effects (DFEs) of available beneficial mutations. By whole genome...

Topics

• Escherichia coli
• Evolution, Molecular
• Genotype
• Mutation
• Selection, Genetic