Article
Shifts in mutation spectra enhance access to beneficial mutations.
Proceedings of the National Academy of Sciences of the United States of America - 30 May 2023
Sane Mrudula, Diwan Gaurav D, Bhat Bhoomika A, Wahl Lindi M, Agashe Deepa
Abstract excerpt
Biased mutation spectra are pervasive, with wide variation in the magnitude of mutational biases that influence genome evolution and adaptation. How do such diverse biases evolve? Our experiments show that changing the mutation spectrum allows populations to sample previously undersampled mutatio...
Topics
- Phylogeny
- Mutation
- Adaptation, Physiological
- Acclimatization
- Genome
- Selection, Genetic
- Evolution, Molecular
