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Article

Impact of individual mutations on increased fitness in adaptively evolved strains of Escherichia coli.

Journal of bacteriology - 1 Jul 2008

Applebee M Kenyon, Herrgård Markus J, Palsson Bernhard Ø

Abstract excerpt

We measured the relative fitness among a set of experimentally evolved Escherichia coli strains differing by a small number of adaptive mutations by directly measuring allelic frequencies in head-to-head competitions using a mass spectrometry-based method. We compared the relative effects of mutations to the same or similar genes acquired in multiple strains when expressed in allele replacement strains. We found...

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Identifiers

PMID: 18487343
DOI: 10.1128/JB.01976-07
PMCID: PMC2447027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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