Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli.

doi:10.1098/rstb.2009.0287

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Article

Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Apr 2010

Trindade Sandra, Perfeito Lilia, Gordo Isabel

Abstract excerpt

Knowledge of the mutational parameters that affect the evolution of organisms is of key importance in understanding the evolution of several characteristics of many natural populations, including recombination and mutation rates. In this study, we estimated the rate and mean effect of spontaneous...

Topics

Computer Simulation
Escherichia coli
Evolution, Molecular
Genetic Fitness
Genetic Variation
Models, Genetic
Monte Carlo Method
Mutation

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