Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli.

Proceedings of the National Academy of Sciences of the United States of America - 25 Sept 2001

Remold S K, Lenski R E

Abstract excerpt

Numerous studies have shown genotype-by-environment (GxE) interactions for traits related to organismal fitness. However, the genetic architecture of the interaction is usually unknown because these studies used genotypes that differ from one another by many unknown mutations. These mutations were also present as standing variation in populations and hence had been subject to prior selection. Based on such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Environment

Share to Escherichia coli

Share to Glucose

Share to Maltose

Share to Selection, Genetic

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 11572987
DOI: 10.1073/pnas.201140198
PMCID: PMC58739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution of individual random mutations to genotype-by-environment interactions in Escherichia coli.PMID 11572987Read ↗

The environment affects epistatic interactions to alter the topology of an empirical fitness landscape.Semantic proximity Read ↗

Pervasive genotype-by-environment interactions shape the fitness effects of antibiotic resistance mutations.Semantic proximity Read ↗

Environment-by-Environment Interactions Differ Across Genetic Backgrounds.Semantic proximity Read ↗

Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG)Semantic proximity Read ↗

Diverse phenotypic and genetic responses to short-term selection in evolving Escherichia coli populations.Semantic proximity Read ↗

Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness.Semantic proximity Read ↗

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment.Semantic proximity Read ↗

Fitness effects of mutations in bacteria.Semantic proximity Read ↗

Epistasis decreases with increasing antibiotic pressure but not temperature.Semantic proximity Read ↗

Genotype-by-environment interactions due to antibiotic resistance and adaptation in Escherichia coli.Semantic proximity Read ↗

High mutation rates limit evolutionary adaptation in Escherichia coli.Semantic proximity Read ↗

The genetic basis of parallel and divergent phenotypic responses in evolving populations of Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.