Article
Association of the DIO2 gene single nucleotide polymorphisms with recurrent depressive disorder.
Acta biochimica Polonica - 1 Jan 2015
Gałecka Elżbieta, Talarowska Monika, Orzechowska Agata, Górski Paweł, Bieńkiewicz Małgorzata, Szemraj Janusz
Abstract excerpt
Genetic factors may play a role in the etiology of depressive disorder. The type 2 iodothyronine deiodinase gene (DIO2) encoding the enzyme catalyzing the conversion of T4 to T3 is suggested to play a role in the recurrent depressive disorder (rDD). The current study investigates whether a specific single nucleotide polymorphism (SNP) of the DIO2 gene, Thr92Ala (T/C); rs 225014 or ORFa-Gly3Asp (C/T); rs 12885300,...
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