Article
Functional polymorphism of cyclooxygenase-2 gene (G-765C) in depressive patients.
Neuropsychobiology - 1 Jan 2010
Gałecki Piotr, Florkowski Antoni, Bieńkiewicz Małgorzata, Szemraj Janusz
Abstract excerpt
BACKGROUND: Depressive disorder (DD) is characterized by an inflammatory process and oxidative stress. Cyclooxygenase-2 (COX-2), the expression of which increases in depression, is an enzyme involved in inflammation and free radical processes. The aim of our study was to assess the correlation between single nucleotide polymorphism G-765C of the COX-2 gene and recurrent DD. METHODS: The study was carried out in a...
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