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Article

Association between inducible and neuronal nitric oxide synthase polymorphisms and recurrent depressive disorder.

Journal of affective disorders - 1 Mar 2011

Gałecki Piotr, Maes Michael, Florkowski Antoni, Lewiński Andrzej, Gałecka Elżbieta, Bieńkiewicz Małgorzata, Szemraj Janusz

Abstract excerpt

BACKGROUND: Major depression is characterised by increased nitric oxide (NO) levels. Inhibition of the NO synthesizing enzymes, neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS), results in antidepressant-like effects, whereas the expression of iNOS and nNOS is increased in depression. Recent studies have indicated that NOS participates in the mechanisms of antidepressants. The aim...

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Source

Identifiers

PMID: 20888049
DOI: 10.1016/j.jad.2010.09.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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