Article
Variation of genes involved in oxidative and nitrosative stresses in depression.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Feb 2018
Wigner Paulina, Czarny Piotr, Synowiec Ewelina, Bijak Michał, Białek Katarzyna, Talarowska Monika, Galecki Piotr, Szemraj Janusz, Sliwinski Tomasz
Abstract excerpt
The dominating hypothesis among numerous hypotheses explaining the pathogenesis of depressive disorders (DD) is the one involving oxidative and nitrosative stress. In this study, we examined the association between single-nucleotide polymorphisms of the genes encoding SOD2 (superoxide dismutase 2), CAT (catalase), GPx4 (glutathione peroxidase 4), NOS1 (nitric oxide synthase 1), NOS2 (nitric oxide synthase 2), and...
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